Kiss of the Spider Woman is two prisoners, Luis Molina and Valentín Arregui, share a cell in a Buenos Aires prison. The story takes place between September 9, 1975 and October 8, 1975. Molina, an effeminate gay window-dresser, is in jail for "corruption of a minor", while Valentín is a political prisoner who is part of a revolutionary group trying to overthrow the government. The two men, seemingly opposites in every way, form an intimate bond in their cell, and their relationship changes both of them in profound ways. Molina recounts various films he has seen to Valentín in order to help them forget their situation.